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para-Bromomethamphetamine (PBMA; developmental code name V-111), also known as 4-bromomethamphetamine (4-BMA), is a monoaminergic drug of the amphetamine family related to para-chloroamphetamine (PCA; 4-chloroamphetamine).
para-Bromoamphetamine (PBA), also known as 4-bromoamphetamine (4-BA), is an amphetamine derivative which acts as a serotonin-norepinephrine-dopamine releasing agent (SNDRA) and produces stimulant effects. Another related compound is para-bromomethamphetamine (PBMA) known by the codename V-111. [1]
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para-Chloromethamphetamine (also known as 4-chloromethamphetamine and 4-CMA) is a stimulant that is the N-methyl derivative and prodrug of the neurotoxic drug para-chloroamphetamine (4-CA). [1] [2] It has been found to decrease serotonin in rats. [3] [4] [5] Further investigation into the long-term effects of chloroamphetamines discovered that ...
Many counties in the Northeast have moderate to high numbers of doctors certified to treat buprenorphine patients. But just 31 percent of the 7,745 doctors in those areas are certified to treat the legal limit of 100 patients.
[3] [5] However, this was found to be due to rapid metabolism in the case of MCA, and inhibiting its metabolism resulted in potent neurotoxicity as with PCA. [5] Conversely, OCA still does not produce apparent neurotoxicity. [5] para-Bromoamphetamine (PBA) and para-bromomethamphetamine (PBMA) show similar serotonergic neurotoxicity to PCA and ...
4-Fluoroamphetamine is a releasing agent and reuptake inhibitor of dopamine, serotonin, and norepinephrine. [9] The respective EC 50 values are 2.0 x 10 −7 M, 7.3 x 10 −7 M, and 0.37 x 10 −7 M, while the IC 50 values are 7.7 x 10 −7 M, 68 x 10 −7 M, and 4.2 x 10 −7 M. [3]