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The Kurtzke Expanded Disability Status Scale (EDSS) is a method of quantifying disability in multiple sclerosis. [1] [2] The scale has been developed by John F. Kurtzke. [1] The EDSS is based on a neurological examination by a clinician. However, a number of versions have been developed which enable patient self-administration. [3]
EDSS can refer to: Elmira District Secondary School , the high school serving the town of Elmira, Ontario, Canada and the surrounding area Expanded Disability Status Scale , a medical scale to monitor the disability changes in multiple sclerosis
John Francis Kurtzke (September 14, 1926 – December 1, 2015) was a neuroepidemiologist and Professor of Neurology at Georgetown University who is best known for his creation of the Expanded Disability Status Scale and for his research on multiple sclerosis (MS). [1]
Within 10 years after the onset of MS one-third of patients reach a score of 6 on the Expanded Disability Status Scale (EDSS), requiring the use of a unilateral walking aid, and by 30 years the proportion increases to 83%. Within five years of onset the EDSS is six in 50% of those with the progressive form of MS. [87]
The main measure of disability and severity is the expanded disability status scale (EDSS), with other measures such as the multiple sclerosis functional composite being increasingly used in research.
Ehlers–Danlos syndromes (EDS) are a group of 13 genetic connective-tissue disorders. [7] Symptoms often include loose joints, joint pain, stretchy velvety skin, and abnormal scar formation. [1]
EDSS (disability status scale), the first scale to monitor MS progression. NEDA (No evidence of disease activity), the new one. Several NEDA criteria have been published. NEDA-3 means that EDSS remains constant, MRI shows no activity and no relapses have appeared. NEDA-4 means NEDA-3 plus that brain atrophy has not increased.
One definition can be based on EDSS score and the time to develop secondary progressive MS (SPMS) (Menon et al., 2013). [ full citation needed ] No consensus exists on the speed of progression or degree of disability sufficient for aggressive MS, but some assume that reaching an EDSS score of 6 points probably represents an upper limit beyond ...