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More specifically, clinical trial data for Zyrtec indicated the following incidence rates for drowsiness and related effects: Drowsiness (14.3%) Fatigue (3.4%) Dizziness (2%) Fatigue and drowsiness are dose-related, meaning higher doses are more likely to cause side effects. For example, the incidence of drowsiness was 11% in those taking ...
Drowsiness; Decreased mental performance; Decrease motor performance; Decreased ability to concentrate; Per the prescribing information for Zyrtec, the overall incidence of sedation and somnolence is around 10-15%. Benadryl causes sedation in more than 20-30% of individuals. The doses of Benadryl used for sleep (50 mg) cause an even higher ...
Zyrtec (cetirizine) Claritin (loratadine) Xyzal (levocetirizine) Second generation antihistamines offer two main benefits over first generation antihistamines (e.g. Benadryl): They typically last 24 hours per dose; They are non-drowsy (with the exception of Zyrtec) Allegra Studies On Drowsiness
Of the above medications, all are non-drowsy except Zyrtec and Xyzal. However, those two are not nearly as sedating as first-generation antihistamines such as Benadryl and Chlor-Trimeton. In addition, even "non-drowsy" antihistamines can cause sedation and drowsiness in a low percentage of users.
Zyrtec can cause drowsiness in a small percentage of people and is therefore not classified as non-drowsy. Specifically, studies show that Claritin (loratadine) and Allegra (fexofenadine) have the lowest rates of drowsiness, with it occurring in 2-4% of patients compared to 22% in patients who take Zyrtec (cetirizine).
Zyrtec (cetirizine) may be taken by patients with high blood pressure, also known as hypertension. Zyrtec (cetirizine) is a once a day antihistamine that is typically well tolerated. Even though it is considered a second generation non-sedating antihistamine, it can still cause drowsiness in some patients.
However, Zyrtec (cetirizine) can cause drowsiness in individuals. In fact, unlike other second generation antihistamines like Claritin, Zyrtec has a high incidence of drowsiness (13.7% of individuals) and fatigue (5.9% of individuals).
Claritin and Zyrtec are both effective drugs to relieve allergy symptoms. However, Zyrtec has been shown to be more effective and work more quickly than Claritin in several studies. Zyrtec does cause more drowsiness than Claritin. Drowsiness occurs in about 22% of people who take Zyrtec compared to 2-4% in those who take Claritin.
First-generation antihistamines, such as Benadryl (diphenhydramine) and Dramamine (dimenhydrinate), are known to cause drowsiness due to their likelihood of crossing the blood-brain barrier. The least sedating antihistamine is thought to be Allegra. Claritin and Zyrtec are generally well tolerated, but may cause drowsiness in some people.
Zyrtec is not classified as non-drowsy as it does cause sedation/drowsiness in around 5-15% of individuals. Nevertheless, the sedation that can occur with it is typically less severe than with 'first-generation' antihistamines. Melatonin With Zyrtec. As mentioned, there is no interaction between the two.