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They can be designed to specifically target cancer biomarkers, allowing for highly sensitive and accurate detection of cancer cells or molecules associated with cancer. Gene therapy: Nanocarriers, such as lipid nanoparticles or polymer nanoparticles, can deliver therapeutic genes to cancer cells. This approach aims to modify the genetic makeup ...
Reduction Sensitive Nanoparticles are used as nanomedicines for drug delivery. As nanocarriers, RSNP can be loaded with drugs for disease therapeutics. [18] This is commonly observed in the use of tumor and cancer treatments. Cancer cells create reducing environments that are used for RSNP activation.
Nanomedicine is the medical application of nanotechnology. [1] Nanomedicine ranges from the medical applications of nanomaterials and biological devices, to nanoelectronic biosensors, and even possible future applications of molecular nanotechnology such as biological machines.
In polymer chemistry, in situ polymerization is a preparation method that occurs "in the polymerization mixture" and is used to develop polymer nanocomposites from nanoparticles. There are numerous unstable oligomers ( molecules ) which must be synthesized in situ (i.e. in the reaction mixture but cannot be isolated on their own) for use in ...
It can be directed to the location of cancer cells with sustained release behavior. Studies have also been done on gold nanoparticle responses to local near-infrared (NIR) light as a stimuli for drug release. In one study, gold nanoparticles functionalized with double-stranded DNA encapsulated with drug molecules, were irradiated with NIR light.
Another cancer related application, though still in mice probing stage, is the use of peptide-coated nanoparticles as activity-based sensors to detect lung cancer. The two main advantages of the use of nanoparticles to detect diseases is that it allows early stage detection, as it can detect tumors the size in the order of millimeters.
Polymer-drug conjugates are drug molecules held in polymer molecules, which act as the delivery system for the drug. Polymer drugs have passed multidrug resistance (MDR) testing and hence may become a viable treatment for endocrine-related cancers. A cocktail of pendant drugs could be delivered by water-soluble polymer platforms.
A recent study looking at the effects of ZnO nanoparticles on human immune cells has found varying levels of susceptibility to cytotoxicity. [144] There are concerns that pharmaceutical companies, seeking regulatory approval for nano-reformulations of existing medicines, are relying on safety data produced during clinical studies of the earlier ...