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Citrate synthase (E.C. 2.3.3.1 (previously 4.1.3.7)) is an enzyme that exists in nearly all living cells. It functions as a pace-making enzyme in the first step of the citric acid cycle (or Krebs cycle). [5] Citrate synthase is located within eukaryotic cells in the mitochondrial matrix, but is encoded by nuclear DNA rather than
Citrate synthase is a member of a small family of enzymes that can directly form a carbon-carbon bond without the presence of metal ion cofactors. It catalyses the first reaction in the Krebs ' cycle, namely the conversion of oxaloacetate and acetyl-coenzyme A into citrate and coenzyme A .
ATP citrate synthase (also ATP citrate lyase (ACLY)) is an enzyme that in animals catalyzes an important step in fatty acid biosynthesis. [2] By converting citrate to acetyl-CoA , the enzyme links carbohydrate metabolism , which yields citrate as an intermediate , with fatty acid biosynthesis , which consumes acetyl-CoA. [ 3 ]
Citrate is an intermediate in the citric acid cycle, also known as the tricarboxylic acid (TCA) cycle or the Krebs cycle, a central metabolic pathway for animals, plants, and bacteria. In the Krebs cycle, citrate synthase catalyzes the condensation of oxaloacetate with acetyl CoA to form citrate.
In biochemistry, a synthase is an enzyme that catalyses a synthesis process. Note that, originally, biochemical nomenclature distinguished synthetases and synthases. Under the original definition, synthases do not use energy from nucleoside triphosphates (such as ATP , GTP , CTP , TTP , and UTP ), whereas synthetases do use nucleoside ...
The CEO of investment firm Azoria lobbied DOGE figurehead Elon Musk to have the department issue stimulus checks from some of the claimed $55 billion in savings.
Synthesis of saturated fatty acids via fatty acid synthase II in E. coli. Straight-chain fatty acid synthesis occurs via the six recurring reactions shown below, until the 16-carbon palmitic acid is produced. [2] [3] The diagrams presented show how fatty acids are synthesized in microorganisms and list the enzymes found in Escherichia coli. [2]
Bird flu is forcing farmers to slaughter millions of chickens a month, pushing U.S. egg prices to more than double their cost in the summer of 2023. While it is fatal to a variety of animals ...