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A meta-analysis for associations between PFASs and human clinical biomarkers for liver injury, analyzing PFAS effects on liver biomarkers and histological data from rodent experimental studies, concluded that evidence exists that PFOA, perfluorohexanesulfonic acid (PFHxS), and perfluorononanoic acid (PFNA) caused hepatotoxicity in humans. [81]
Story at a glance A group of potentially harmful chemicals called per- and polyfluoroalkyl substances (PFAS) have repeatedly cropped up in headlines. But the sheer number of chemicals in this ...
2017 PFAS are on the Government of Canada's 2019 chart of substances prohibited by the Canadian Environmental Protection Act, 1999 (CEPA) and by the Prohibition of Certain Toxic Substances Regulations, 2012. These substances are under these regulations because they are "among the most harmful" and "have been declared toxic to the environment ...
The observed probable serious effects for human health and the environment are thyroid hormonal disturbances and reproductive toxicity seen in rodents, and effects on liver, kidney and haematological system in rats, hormonal disturbances and effects on reproduction in marine medaka fish and effects on expression of hormone receptors in tadpoles.
Per and polyfluorinated alkyl substances, or PFAS, are chemicals that linger in the body and are linked to health issues like cancer, obesity, liver damage, decreased fertility, thyroid disease ...
The monomers of such perfluoroalkoxy alkane polymers, in common with other per- and polyfluoroalkyl substances, are widespread in the environment due to human production and release of the chemicals; so durable that they are referred to as "forever chemicals"; and have detrimental health concerns not yet fully understood. [10]
PFAS has been found in almost all human blood samples tested, one study found 97% of Americans has PFAS in their blood. [29] PFAS chemicals have been linked to high cholesterol, [ 30 ] altered kidney and thyroid function, [ 31 ] ulcerative colitis, [ 32 ] immunosuppression, [ 33 ] decreased effectiveness of vaccines, [ 34 ] low birth weight ...