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Heart valves can malfunction for a variety of reasons, which can impede the flow of blood through the valve and/or let blood flow backwards through the valve (regurgitation). Both processes put strain on the heart and may lead to serious problems, including heart failure. While some dysfunctional valves can be treated with drugs or repaired ...
A heart valve is a biological one-way valve that allows blood to flow in one direction through the chambers of the heart. A mammalian heart usually has four valves. Together, the valves determine the direction of blood flow through the heart. Heart valves are opened or closed by a difference in blood pressure on each side. [1] [2] [3]
A valve prolapse can result in mitral insufficiency, which is the regurgitation or backflow of blood from the left ventricle to the left atrium due to the incomplete closure of the valve causing a systolic murmur heard at the apex of the heart. This increase in pressure in the left atrium and pulmonary circuit can lead to symptoms like fatigue ...
The lumped parameter model consists in a system of ordinary differential equations that adhere to the principles of conservation of mass and momentum balance. The model is obtained exploiting the electrical analogy where the current represents the blood flow, the voltage represents the pressure difference, the electric resistance plays the role of the vascular resistance (determined by the ...
In vertebrates, the circulatory system is a system of organs that includes the heart, blood vessels, and blood which is circulated throughout the body. [1] [2] It includes the cardiovascular system, or vascular system, that consists of the heart and blood vessels (from Greek kardia meaning heart, and Latin vascula meaning vessels).
The valve of the coronary sinus is a thin, semilunar (half-moon-shaped) valve located on the anteroinferior part of the opening into the right atrium. [5] It is formed by a semicircular fold of the lining membrane of the right atrium. It is situated at the base of the inferior vena cava. [citation needed]
The valve is repositionable before release to ensure accurate placement helping to improve patient outcomes. [12] Edwards' Sapien aortic valve is made from bovine pericardial tissue and is implanted via a catheter-based delivery system. It is approved by the FDA for use in the US. [10] [11] [12]
Tissue engineered heart valves (TEHV) offer a new and advancing proposed treatment of creating a living heart valve for people who are in need of either a full or partial heart valve replacement. Currently, there are over a quarter of a million prosthetic heart valves implanted annually, [ 1 ] and the number of patients requiring replacement ...