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Common side effects include headache, abdominal pain, diarrhea or constipation, and dizziness. [4] Serious side effects may include pneumonia and seizures. [4] [5] Use in pregnancy appears safe but has not been well studied, while use during breastfeeding is not recommended. [1] Famotidine was patented in 1979 and came into medical use in 1985. [6]
These side effects are serious and some of them are permanent, and many remain a crucial concern for companies and healthcare professionals and substantial efforts are being encouraged to reduce the potential risks for future antipsychotics through more clinical trials and drug development.
Long-term use is sometimes described as use not shorter than three months. [2] Benzodiazepines are generally effective when used therapeutically in the short term, [3] but even then the risk of dependency can be significantly high. There are significant physical, mental and social risks associated with the long-term use of benzodiazepines. [3]
According to research cited in the FDA’s prescribing information for Ozempic, some of the severe side effects and long-term risks include: Pancreatitis. Acute kidney injury.
Type A: augmented pharmacological effects, which are dose-dependent and predictable [5]; Type A reactions, which constitute approximately 80% of adverse drug reactions, are usually a consequence of the drug's primary pharmacological effect (e.g., bleeding when using the anticoagulant warfarin) or a low therapeutic index of the drug (e.g., nausea from digoxin), and they are therefore predictable.
It wasn't until a decade later that Sharp came to believe the still-noticeable bulges were from a little-discussed potential risk of CoolSculpting, known as paradoxical adipose hyperplasia (PAH).
The term "torsades de pointes" is translated from French as "twisting of the peaks" because the complexes appear to undulate, or twist around, the EKG baseline. TdP can be acquired by inheritance of a congenital long QT syndrome, or more commonly from the ingestion of a pharmacologic drug. During TdP episodes, patients have a heart rate of 200 ...
Because of its hormonal effects, cimetidine rarely may cause sexual dysfunction including loss of libido and erectile dysfunction and gynecomastia (0.1–0.2%) in males during long-term treatment. [16] [17] [18] Rarely, interstitial nephritis, urticaria, and angioedema have been reported with cimetidine treatment. [16]
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