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H-band is the zone of the thick filaments that has no actin. Within the H-zone is a thin M-line (from the German "mittel" meaning middle), appears in the middle of the sarcomere formed of cross-connecting elements of the cytoskeleton. Molecular model of the Sarcomere in the A-band. Organization of the central region of the A-band (C-zone).
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the backbone of a muscle fibre is actin filaments which extend from the Z line up to one end of the H zone, where they are attached to an elastic component which they named "S filament"; myosin filaments extend from one end of the A band through the H zone up to the other end of the A band;
The darker bands within skeletal muscle, known as anisotropic bands (A bands), encompass both thick and thin filaments and constitute the central region of the sarcomere, extending across the H-zone. Collectively, the A bands and the I bands create the distinctive striped appearance of skeletal muscle tissue. [ 3 ]
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[3] (a) electron micrograph of mouse heart muscle sarcomere. (b) diagram of sarcomere layout from (a). Myosin thick filaments are blue, thin actin filaments are orange, Z-discs are black, and the M-band is grey/white. (c) schematic of M-band composition of M-lines. (d) M-band hexagonal lattice based on electron microscopy sections.
The names of the various sub-regions of the sarcomere are based on their relatively lighter or darker appearance when viewed through the light microscope. Each sarcomere is delimited by two very dark colored bands called Z-discs or Z-lines (from the German zwischen meaning between). These Z-discs are dense protein discs that do not easily allow ...
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