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Medication discontinuation is the ceasing of a medication treatment for a patient by either the clinician or the patient themself. [ 1 ] [ 2 ] When initiated by the clinician, it is known as deprescribing . [ 3 ]
Drug withdrawal, drug withdrawal syndrome, or substance withdrawal syndrome [1] is the group of symptoms that occur upon the abrupt discontinuation or decrease in the intake of pharmaceutical or recreational drugs. In order for the symptoms of withdrawal to occur, one must have first developed a form of drug dependence.
A drug holiday (sometimes also called a drug vacation, medication vacation, structured treatment interruption, tolerance break, treatment break or strategic treatment interruption) is when a patient stops taking a medication(s) for a period of time; anywhere from a few days to many months or even years if the doctor or medical provider feels it is best for the patient.
The rebound effect, or pharmaceutical rebound phenomenon, is the emergence or re-emergence of symptoms that were either absent or controlled while taking a medication, but appear when that same medication is discontinued, or reduced in dosage. In the case of re-emergence, the severity of the symptoms is often worse than pretreatment levels.
“The College has produced a resource for patients and carers on stopping antidepressants, that offers information on how someone can taper their medication at a pace that suits them and their ...
This is a general list of long-term side effects associated with Antipsychotic (neuroleptic) medication. ... This page was last edited on 23 February 2025, ...
After the last dose has been taken, the acute phase of the withdrawal generally lasts for about two months although withdrawal symptoms, even from low-dose use, can persist for six to twelve months gradually improving over that period, [123] [68] however, clinically significant withdrawal symptoms may persist for years, although gradually ...
For instant-release morphine (shorter duration of action), withdrawal symptoms begin 8 to 24 hours after the last dose and persist for 4 to 10 days. For extended-release morphine (longer duration of action), withdrawal symptoms begin 12 to 48 hours after the last dose and persist for 10 to 20 days. [12]