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  2. Intravascular volume status - Wikipedia

    en.wikipedia.org/wiki/Intravascular_volume_status

    Renal causes include overuse of diuretics, or trauma or disease of the kidney. Extrarenal causes include bleeding, burns, and any causes of edema (e.g. congestive heart failure, liver failure). [citation needed] Intravascular volume depletion is divided into three types based on the blood sodium level:

  3. Reference ranges for blood tests - Wikipedia

    en.wikipedia.org/wiki/Reference_ranges_for_blood...

    In contrast, optimal (health) range or therapeutic target is a reference range or limit that is based on concentrations or levels that are associated with optimal health or minimal risk of related complications and diseases. For most substances presented, the optimal levels are the ones normally found in the population as well.

  4. Heart failure - Wikipedia

    en.wikipedia.org/wiki/Heart_failure

    Heart failure (HF), also known as congestive heart failure (CHF), is a syndrome caused by an impairment in the heart's ability to fill with and pump blood. Although symptoms vary based on which side of the heart is affected, HF typically presents with shortness of breath, excessive fatigue, and bilateral leg swelling. [3]

  5. Blood volume - Wikipedia

    en.wikipedia.org/wiki/Blood_volume

    Total Blood Volume has been measured manually by the use of carbon monoxide (CO) as a tracer for more than 100 years and was first proposed by French scientists Grehant and Quinquaud in 1882. Soon after a usable set-up for human use was developed by Oxford scientists John Haldane and Lorrain Smith and presented in the Journal of Physiology in 1900.

  6. Blood plasma - Wikipedia

    en.wikipedia.org/wiki/Blood_plasma

    Serum sample preparation requires about 30 minutes of waiting time before it can be centrifuged and then analyzed. [23] However, coagulation can be hastened down to a few minutes by adding thrombin or similar agents to the serum sample. [25] Compared to serum, 15–20% larger volume of plasma can be obtained from a blood sample of certain size.

  7. Volume of distribution - Wikipedia

    en.wikipedia.org/wiki/Volume_of_distribution

    Volume of distribution may be increased by kidney failure (due to fluid retention) and liver failure (due to altered body fluid and plasma protein binding). Conversely it may be decreased in dehydration. The initial volume of distribution describes blood concentrations prior to attaining the apparent volume of distribution and uses the same ...

  8. List of human blood components - Wikipedia

    en.wikipedia.org/wiki/List_of_human_blood_components

    In plasma or serum (g/cm 3) Water: Solvent 0.81-0.86 0.93-0.95 Acetoacetate: Produced in liver 8-40 × 10 −7: 4-43 × 10 −7: Acetone: product of bodyfat breakdown 3-20 × 10 −6: Acetylcholine: Neurotransmitter of the parasympathetic nervous system: 6.6-8.2 × 10 −8: Adenosine triphosphate: Energy storage total 3.1-5.7 × 10 −4 ...

  9. Blood plasma fractionation - Wikipedia

    en.wikipedia.org/wiki/Blood_plasma_fractionation

    Albumin constitutes about 60% of the total protein in plasma and is present at concentrations between 35 and 55 mg/mL. [2] It is the main contributor to osmotic pressure of the blood and it functions as a carrier molecule for molecules with low water solubility such as lipid-soluble hormones , enzymes , fatty acids , metal ions, and ...