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Ipratropium bromide/salbutamol, sold under the brand name Combivent among others, is a combination medication used to treat chronic obstructive pulmonary disease (COPD). [ 1 ] [ 4 ] [ 5 ] It contains ipratropium (an anticholinergic ) and salbutamol (albuterol, a β 2 -adrenergic agonist ).
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Inhaled ipratropium does not decrease mucociliary clearance. [21] The inhalation itself can cause headache and irritation of the throat in a few percent of patients. [20] Urinary retention has been reported in patients receiving doses by nebulizer. As a result, caution may be warranted, especially by men with prostatic hypertrophy. [23]
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Dr Siegle's steam nebulizer, Thackray Museum of Medicine [27] The first pneumatic nebulizer fed from an electrically driven gas (air) compressor was invented in the 1930s and called a Pneumostat. With this device, a medical liquid (typically epinephrine chloride , used as a bronchial muscle relaxant to reverse constriction). [ 28 ]
An inhaler (puffer, asthma pump or allergy spray) is a medical device used for delivering medicines into the lungs through the work of a person's breathing. This allows medicines to be delivered to and absorbed in the lungs, which provides the ability for targeted medical treatment to this specific region of the body, as well as a reduction in the side effects of oral medications.
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