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Factor XII deficiency is a deficiency in the production of factor XII (FXII), a plasma glycoprotein and clotting factor that participates in the coagulation cascade and activates factor XI. FXII appears to be not essential for blood clotting, as individuals with this condition are usually asymptomatic and form blood clots in vivo .
Factor XII deficiency is a rare disorder that is inherited in an autosomal recessive manner. [19] Unlike other clotting factor deficiencies, factor XII deficiency is totally asymptomatic and does not cause excess bleeding. [19] Mice lacking the gene for factor XII, however, are less susceptible to thrombosis. The protein seems to be involved in ...
Hypoprothrombinemia can be the result of a genetic defect, may be acquired as the result of another disease process, or may be an adverse effect of medication.For example, 5-10% of patients with systemic lupus erythematosus exhibit acquired hypoprothrombinemia due to the presence of autoantibodies which bind to prothrombin and remove it from the bloodstream (lupus anticoagulant ...
Cognitive dysfunction syndrome in dogs is an established diagnosis, but there has been limited research for cats and treatment options are limited. [13] Drugs used for treatment of the disease have been approved for use in dogs. However, they are used off-label in treatment of cats. [1] Early diagnosis improves results of long-term treatment. [6]
Treatment depends on the type and cause of the hemolytic anemia. [ 2 ] Symptoms of hemolytic anemia are similar to other forms of anemia ( fatigue and shortness of breath ), but in addition, the breakdown of red cells leads to jaundice and increases the risk of particular long-term complications, such as gallstones [ 4 ] and pulmonary ...
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Malnutrition in cats is currently uncommon due to complete and balanced diets being formulated and fed. [12] Yet it can still occur if the cat's food intake decreases beyond what the food can provide, if interactions occur between ingredients or nutrients, if mistakes are made during formulation or manufacturing, and if the food is stored for a ...
Wills factor, FA , N-(4-{[(2-amino-4 ... to be tested for vitamin B 12 deficiency before treatment with ... if a risk of folate deficiency is indicated. Cats with ...