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Proanthocyanidins are a class of polyphenols found in many plants, such as cranberry, blueberry, and grape seeds. Chemically, they are oligomeric flavonoids. Many are oligomers of catechin and epicatechin and their gallic acid esters. More complex polyphenols, having the same polymeric building block, form the group of condensed tannins.
A 2016 meta-analysis concluded that grape seed extract, in a dose of under 800 milligrams per day over at least 8 weeks, might help to reduce systolic and diastolic blood pressure. [7] People with metabolic syndrome had a more significant outcome (average of a 8½ mmHg decrease in systolic blood pressure) than in healthy subjects. [7]
The Porter Assay is a chemical test to help determine the potency of procyanidin containing compounds, such as grape seed extract. It is an acid hydrolysis, which splits larger chain units (dimers and trimers) into single unit monomers and oxidizes them. This leads to a colour change, which can be measured using a spectrophotometer. The greater ...
The term polyphenol is not well-defined, but it is generally agreed that they are natural products with "several hydroxyl groups on aromatic rings" including four principal classes: "phenolic acids, flavonoids, stilbenes, and lignans". [5] Flavonoids include flavones, flavonols, flavanols, flavanones, isoflavones, proanthocyanidins, and ...
Grape therapy or grape diet, also known as ampelotherapy, is a diet that involves heavy consumption of grapes, including seeds, and parts of the vine, including leaves, that is a form of alternative medicine. The concept was developed in 19th-century Germany in spas such as Bad Duerkheim and Merano. [1]
The results were also more pronounced in women. “Findings highlight the potential role of diet quality in pain management and function, particularly in women,” the researchers concluded.
In a 2010 review of scientific evidence concerning the possible health benefits of eating foods claimed to have "antioxidant properties" due to anthocyanins, the European Food Safety Authority concluded that 1) there was no basis for a beneficial antioxidant effect from dietary anthocyanins in humans, 2) there was no evidence of a cause-and ...
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