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  2. Rosuvastatin - Wikipedia

    en.wikipedia.org/wiki/Rosuvastatin

    [citation needed] Annual cost to the UK National Health Service (NHS) in 2018, for 5–40 mg rosuvastatin daily (of one person) was £24-40, compared to £10-20 for 20–80 mg simvastatin. [38] In 2013, it was the fourth-highest selling drug in the United States, accounting for approximately $5.2 billion in sales. [39]

  3. Statin - Wikipedia

    en.wikipedia.org/wiki/Statin

    Guidelines by the American College of Cardiology and the American Heart Association recommend statin treatment for primary prevention of cardiovascular disease in adults with LDL cholesterol ≥ 190 mg/dL (4.9 mmol/L) or those with diabetes, age 40–75 with LDL-C 70–190 mg/dL (1.8–4.9 mmol/dL); or in those with a 10-year risk of developing ...

  4. Ezetimibe/rosuvastatin - Wikipedia

    en.wikipedia.org/wiki/Ezetimibe/rosuvastatin

    KEGG. D11520. Ezetimibe/rosuvastatin, sold under the brand name Ridutrin among others, is a combination medication used to treat high cholesterol. [6][7] In some countries it is sold as a kit or a pack containing two distinct pills. [8][9] The combination was approved for medical use in the United States in March 2021.

  5. JUPITER trial - Wikipedia

    en.wikipedia.org/wiki/JUPITER_trial

    JUPITER was a randomized double-blind placebo-controlled study investigating the use of rosuvastatin in the primary prevention of cardiovascular disease.The trial focused on patients with normal low-density lipoprotein (LDL) cholesterol levels but increased levels of high-sensitivity C-reactive protein (hs-CRP).

  6. Ezetimibe - Wikipedia

    en.wikipedia.org/wiki/Ezetimibe

    Ezetimibe. Ezetimibe, sold under the brand name Zetia among others, is a medication used to treat high blood cholesterol and certain other lipid abnormalities. [3][4] Generally it is used together with dietary changes and a statin. [5] Alone, it is less preferred than a statin. [4] It is taken by mouth. [4]

  7. Atorvastatin - Wikipedia

    en.wikipedia.org/wiki/Atorvastatin

    [104] [108] [110] [111] [112] Warner-Lambert management was concerned that atorvastatin was a me-too version of rival Merck & Co.'s orphan drug lovastatin (brand name Mevacor). Mevacor, which was first marketed in 1987, was the industry's first statin and Merck's synthetic version – simvastatin – was in the advanced stages of development. [109]

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  9. Fenofibrate - Wikipedia

    en.wikipedia.org/wiki/Fenofibrate

    Fenofibrate (sold under the brand name Tricor among others, is an oral medication of the fibrate class used to treat abnormal blood lipid levels. [3] It is less commonly used compared than statins because it treats a different type of cholesterol abnormality to statins. While statins have strong evidence for reducing heart disease and death ...

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