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Synthetic cannabinoids were made for cannabinoid research focusing on tetrahydrocannabinol (THC), cannabinoid receptors, and the endocannabinoids that activate them in the body. Synthetic cannabinoids were needed partly due to legal restrictions on natural cannabinoids, which make them difficult to obtain for research.
HU-210 has a binding affinity of 0.061 nM at CB 1 and 0.52 nM at CB 2 in cloned human cannabinoid receptors [7] compared to delta-9-THC of 40.7 nM at CB 1. [ 8 ] HU-210 is the (–)-1,1-dimethylheptyl analog of 11-hydroxy- Δ 8 - tetrahydrocannabinol; in some references it is called 1,1-dimethylheptyl- 11-hydroxytetrahydrocannabinol.
Nabiximols (USAN) [2] sold under the brand name Sativex, is a specific Cannabis extract that was approved in 2010 as a botanical drug in the United Kingdom. Nabiximols is sold as a mouth spray intended to alleviate neuropathic pain, spasticity, overactive bladder, and other symptoms of multiple sclerosis; it was developed by the UK company GW ...
CBD shares a precursor with THC and is the main cannabinoid in CBD-dominant Cannabis strains. CBD has been shown to play a role in preventing the short-term memory loss associated with THC. [29] There is tentative evidence that CBD has an anti-psychotic effect, but research in this area is limited. [30] [24]
It is the principal psychoactive constituent of cannabis and one of at least 113 total cannabinoids identified on the plant. Although the chemical formula for THC (C 21 H 30 O 2) describes multiple isomers, [10] the term THC usually refers to the delta-9-THC isomer with chemical name (−)-trans-Δ9-tetrahydrocannabinol.
Are you thinking about trying a CBD spray for pain? There are two kinds of CBD sprays to choose from: Those that are sprayed into the mouth for fast, system-wide absorption through the mucous ...
THC-O-acetate (THC acetate ester, O-acetyl-THC, THC-O, AcO-THC) is the acetate ester of THC. The term THC-O-acetate and its variations are commonly used for two types of the substance, dependent on which cannabinoid it is synthesized from. The difference between Δ 8 -THC and Δ 9 -THC is bond placement on the cyclohexene ring.
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