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As aging is the primary risk factor for major human diseases, including cancer, diabetes, cardiovascular disorders, and neurodegenerative diseases, it is important to describe and classify the types of changes that it entails. After a decade, the authors of the heavily cited original paper updated the set of proposed hallmarks in January 2023.
Ageing (or aging in American English) is the process of becoming older. The term refers mainly to humans, many other animals, and fungi, whereas for example, bacteria, perennial plants and some simple animals are potentially biologically immortal. [ 1 ] In a broader sense, ageing can refer to single cells within an organism which have ceased ...
For example, in the United States, being healthy, physically, and socially active are signs of a good old age. On the other hand, Africans focus more on food and material security and a helpful family when describing old age well-being. [111] Additionally, Koreans are more anxious about aging and more scared of old people than Americans are. [112]
Alzheimer's disease (AD) is a neurodegenerative disease that usually starts slowly and progressively worsens, [ 2 ] and is the cause of 60–70% of cases of dementia. [ 2 ][ 15 ] The most common early symptom is difficulty in remembering recent events. [ 1 ] As the disease advances, symptoms can include problems with language, disorientation ...
A Stanford study found humans experience rapid aging at 44 and 60 due to significant molecular changes, challenging the idea that aging is a gradual process. Humans Are Rapidly Aging at 44 and 60 ...
Normal aging is associated with a decline in various memory abilities in many cognitive tasks; the phenomenon is known as age-related memory impairment (AMI) or age-associated memory impairment (AAMI). The ability to encode new memories of events or facts and working memory shows decline in both cross-sectional and longitudinal studies. [8]
Fewer cancers and avoiding typical signs of aging with treatment. Unlike previously proposed life-extending drugs and treatments, which often have poor side-effect profiles, work in only one sex ...
Biogerontology is the sub-field of gerontology concerned with the biological aging process, its evolutionary origins, and potential means to intervene in the process. The term "biogerontology" was coined by S. Rattan, and came in regular use with the start of the journal Biogerontology in 2000. It involves interdisciplinary research on the ...