Search results
Results from the WOW.Com Content Network
Patients with proximal (limb-girdle) weakness may have difficulty rising from a chair, climbing stairs, or lifting their arms overhead to perform activities of daily living (e.g., combing...
Most myopathies share the common symptom of symmetric muscle weakness (similar on both sides of your body), especially in proximal muscles. Proximal muscles are those closest to the center of your body, such as the muscles in your shoulders, upper arms, hips and thighs.
Proximal myopathy presents as generalized muscle weakness commonly involving the muscles of upper and/or lower limbs. Toxins, long-term use of statins, corticosteroids, alcohol, SGLT2 inhibitors, COVID-19 vaccination, and antimalarials have been attributed to its development.
Polymyositis (pol-e-my-o-SY-tis) is an uncommon inflammatory disease that causes muscle weakness affecting both sides of your body. Having this condition can make it difficult to climb stairs, rise from a seated position, lift objects or reach overhead.
This 38-year-old woman likely has a myopathy given the symmetrical pattern of proximal weakness involving legs and arms. The differential diagnosis includes an acquired (e.g., inflammatory or toxic myopathy) or genetic (e.g., muscular dystrophy, late-onset congenital myopathy or metabolic myopathy) myopathic disorder.
Symmetrical proximal muscle weakness, wasting, normal sensation, and normal stretch reflexes are classical findings in patients with myopathies particularly in IIM and myopathies associated with CTD. Aching muscle cramps can also occur.
Aging, fatigue, recovery from intense exercise or strength training, poor physical conditioning, and taking certain medications can cause muscle weakness. It can also be caused by an underlying immune condition, a virus, or a neurological problem.
diagnosis of true muscle weakness is extensive, including neurologic, rheumatologic, endocrine, genetic, medication- or toxin-related, and infectious etiologies.
Proximal muscle weakness impairs reaching upward (eg, combing hair, lifting objects over the head), ascending stairs, or getting up from a sitting position; this pattern is typical of inflammatory myopathies.
General signs and symptoms of myopathy include the following: Symmetric proximal muscle weakness. Malaise, fatigue. Dark-colored urine (suggests myoglobinuria) and/or fever. Absence of sensory...