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Dapoxetine, sold under the brand name Priligy among others, is a selective serotonin reuptake inhibitor (SSRI) used for the treatment of premature ejaculation (PE) in men ages 18 to 64 years old. [ 3 ] [ 4 ] [ 5 ] Dapoxetine works by inhibiting the serotonin transporter , increasing serotonin's action at the postsynaptic cleft, and as a ...
Premature ejaculation (PE) is a male sexual dysfunction that occurs when a male expels semen (and most likely experiences orgasm) soon after beginning sexual activity, and with minimal penile stimulation. [1] It has also been called early ejaculation, rapid ejaculation, rapid climax, premature climax and (historically) ejaculatio praecox.
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English: Complete demonstration of the orgasm process of an adult male. The subject is a 27-year-old healthy circumcised Caucasian male. The video begins with the subject's genitals in a non-aroused flaccid state (0:00).
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English: Real-time demonstration of the production of male pre-ejaculatory fluid. The subject is a 27-year-old healthy circumcised Caucasian male whose genitals are in a state of mild sexual arousal.
Common ejaculatory disorders include: premature ejaculation, retrograde ejaculation, delayed ejaculation, anejaculation, inhibited ejaculation, and anorgasmia. [ 2 ] See also
Numerous chemical substances influence the IELT. Substances such as alcohol and opioids (e.g. heroin, morphine, oxycodone) depress the central nervous system, prolonging the IELT, while selective serotonin reuptake inhibitors (SSRIs) (e.g. dapoxetine) delay ejaculation by blocking a physiological process connected to ejaculatory inevitability, "the male point of no return".
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