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They can be designed to specifically target cancer biomarkers, allowing for highly sensitive and accurate detection of cancer cells or molecules associated with cancer. Gene therapy: Nanocarriers, such as lipid nanoparticles or polymer nanoparticles, can deliver therapeutic genes to cancer cells. This approach aims to modify the genetic makeup ...
Polymer-drug conjugates are drug molecules held in polymer molecules, which act as the delivery system for the drug. Polymer drugs have passed multidrug resistance (MDR) testing and hence may become a viable treatment for endocrine-related cancers. A cocktail of pendant drugs could be delivered by water-soluble polymer platforms.
Nanoparticles of natural polymers such as chitosan are commonly used adjuvants in modern vaccine formulations. [63] Ceria nanoparticles appear very promising for both enhancing vaccine responses and mitigating inflammation, as their adjuvanticity can be adjusted by modifying parameters such as size, crystallinity, surface state, and stoichiometry.
It can be directed to the location of cancer cells with sustained release behavior. Studies have also been done on gold nanoparticle responses to local near-infrared (NIR) light as a stimuli for drug release. In one study, gold nanoparticles functionalized with double-stranded DNA encapsulated with drug molecules, were irradiated with NIR light.
A Pilot Study of AuroLase™ Therapy (gold nano shells) in refractory and/or recurrent tumors of the head and neck was completed in 2009 [a] and two trials are currently using AuroLase™ therapy for the treatment of primary/metastatic lung cancer [b] and for prostate cancer. [c] Other gold nanoparticles on the market are mostly for synthesis ...
The Journal of Nanoparticle Research is a monthly peer-reviewed scientific journal published by Springer Science+Business Media, part of Springer-Nature (springernature.com).
Polymer nanoscience is the study and application of nanoscience to polymer-nanoparticle matrices, where nanoparticles are those with at least one dimension of less than 100 nm. The transition from micro- to nano-particles lead to change in its physical as well as chemical properties.
Nanofibers are under study as a possible drug carrier candidate. [9] [10] [70] Natural polymers such as gelatin and alginate make for good fabrication biomaterials for carrier nanofibers because of their biocompatibility and biodegradability that result in no harm to the tissue of the host and no toxic accumulation in the human body ...