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Fenofibrate (sold under the brand name Tricor among others), is an oral medication of the fibrate class used to treat abnormal blood lipid levels. [3] It is less commonly used compared to statins because it treats a different type of cholesterol abnormality to statins.
Most fibrates can cause mild stomach upset and myopathy (muscle pain with CPK elevations). Fibrates decrease the synthesis of bile acid by down-regulation of cholesterol 7 alpha-hydroxylase and sterol 27-hydroxylase expression, therefore making it easier for cholesterol to precipitate and increasing the risk for gallstones.
Fenofibrate is a peroxisome proliferator-activated receptor (PPAR) agonist. [2] It activates a type of receptor called the peroxisome proliferator-activated receptor alpha , which is involved in breaking down fat from the diet, especially triglycerides. [ 2 ]
Fenofibrate/simvastatin, sold under the brand name Cholib, is a fixed-dose combination medication used to treat abnormal blood lipid levels when used in combination ...
The Complaint Resolution Program helps resolve complaints that consumers have filed after experiencing difficulty or disappointment in the California marketplace. The Consumer information Center is DCA's information resource center for consumers and licensees. Through its Call Center and Correspondence Unit, CIC provides consumers and licensees ...
Gemfibrozil, sold under the brand name Lopid among others, is a medication used to treat abnormal blood lipid levels. [3] It is generally less preferred than statins. [3] [4] Use is recommended together with dietary changes and exercise. [3]
A 2013 Cochrane review found a decrease in risk of death and other poor outcomes without any evidence of harm. [4] For every 138 people treated for 5 years, one fewer dies; for every 49 treated, one fewer has an episode of heart disease. [11] A 2011 review reached similar conclusions, [25] and a 2012 review found benefits in both women and men ...
Whole, dietary forms of fibre are more difficult to ingest and absorb than milled and refined food products. [17] This is because dietary fibre may be able to displace available calories and nutrients , requires more time for chewing (thereby slowing intake rate and inducing satiety ), and reduces the efficiency of absorption in the small ...