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Huntington's disease (HD), also known as Huntington's chorea, is an incurable neurodegenerative disease [7] that is mostly inherited. [8] The earliest symptoms are often subtle problems with mood or mental/psychiatric abilities. [9] [1] A general lack of coordination and an unsteady gait often follow. [2]
Huntingtin (Htt) is the protein coded for in humans by the HTT gene, also known as the IT15 ("interesting transcript 15") gene. [5] Mutated HTT is the cause of Huntington's disease (HD), and has been investigated for this role and also for its involvement in long-term memory storage.
In the 1967 film Valley of the Dolls, Tony Polar, the singer married to Jennifer North, has Huntington's Chorea.; Arlo Guthrie's 1969 film Alice's Restaurant, which depicts Guthrie's father Woody suffering from what was then called "Huntington's Chorea", and features numerous mentions of the condition by the younger Guthrie to his peers and the draft board's medical staff.
The Society comprises 50+ volunteer-led local chapters and affiliates across the country with its headquarters in New York City. Additionally, HDSA hosts more than 200 support groups for people with HD, their families, caregivers and people at-risk, and is a resource on Huntington's Disease for medical professionals and the general public. [1]
HOPES Logo. The Huntington's disease Outreach Project for Education at Stanford (HOPES) is a student-run project at Stanford University dedicated to making scientific information about Huntington's disease (HD) more readily accessible to patients and the public.
The film begins at a dinner party. Filmmaker and actress Marianna Palka, 33 years old, is joined by friends in anticipation of the genetic testing results she will receive the next day, revealing whether or not she has inherited the presently untreatable neurodegenerative illness, Huntington's disease, from her father, who has the illness.
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