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Although DISH manifests in a similar manner to ankylosing spondylitis, they are separate diseases. Ankylosing spondylitis is a genetic disease with identifiable marks, tends to start showing signs in adolescence or young adulthood, is more likely to affect the lumbar spine, and affects organs.
Ankylosing spondylitis patients are particularly prone to developing syndesmophytes. [2] They are also commonly seen in patients who have had back surgery or other chronic stresses on the ligaments of their spine.
Ankylosing spondylitis (AS) is a type of arthritis from the disease spectrum of axial spondyloarthritis. [5] It is characterized by long-term inflammation of the joints of the spine, typically where the spine joins the pelvis. [2]
X-ray showing osteophytes of spondylosis of the lumbar spine. A range of bone-formation processes are associated with aging, degeneration, mechanical instability, and disease (such as diffuse idiopathic skeletal hyperostosis). Osteophyte formation has classically been related to sequential and consequential changes in such processes.
Since the disease ankylosing spondylitis was still defined by the Modified New York criteria of 1984, there was the need to find a new disease term that would also include the less severe forms or early onset of ankylosing spondylitis. This expression was found in the umbrella term axial spondyloarthritis.
HLA-B27 is a polymorphic form of the HLA-B molecule found in up to 95% of people with ankylosing spondylitis of European ancestry, [16] [17] 70% with reactive arthritis, [18] 60% with psoriatic spondylitis, [12] 25% with peripheral psoriatic arthritis, [17] and 70% with spondylitis associated with inflammatory bowel disease.
In radiology, a Romanus lesion is the erosion of the anterior and posterior vertebral endplates in patients with an inflammatory spondyloarthropathy – such as ankylosing spondylitis or an enteropathic arthropathy.
Spondylitis is an inflammation of the vertebrae. It is a form of spondylopathy . In many cases, spondylitis involves one or more vertebral joints , as well, which itself is called spondylarthritis .
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