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By definition, they are greater than 4 mm in largest dimension; smaller lesions are referred to as pulmonary carcinoid tumourlets. [citation needed] The differential diagnosis of typical pulmonary carcinoid tumour includes: atypical pulmonary carcinoid tumour, pulmonary carcinoid tumourlet and lung adenocarcinoma. [citation needed]
Pulmonary carcinoid tumour is a neuroendocrine tumour of the lung. [1] There are two types: Typical pulmonary carcinoid tumour; ... Lung carcinoids (cancer.org)
A carcinoid (also carcinoid tumor) is a slow-growing [1] type of neuroendocrine tumor originating in the cells of the neuroendocrine system. In some cases, metastasis may occur. Carcinoid tumors of the midgut ( jejunum , ileum , appendix , and cecum ) are associated with carcinoid syndrome .
Enterochromaffin cells, which give rise to carcinoid tumors, were identified in 1897 by Nikolai Kulchitsky and their secretion of serotonin was established in 1953 [105] when the "flushing" effect of serotonin had become clinically recognized. Carcinoid heart disease was identified in 1952, and carcinoid fibrosis in 1961. [105]
It is an uncommon low-grade malignant lung mass that is most often in the central airways of the lung. It is also known as "atypical lung carcinoid tumour", " atypical lung carcinoid" or "moderately differentiated neuroendocrine carcinoma". It is a more aggressive than typical carcinoid tumors: nodal metastases in 70% vs. 5%.
The American Joint Committee on Cancer and the International Union Against Cancer recommend TNM staging, using a uniform scheme for NSCLC, SCLC, and bronchopulmonary carcinoid tumors. [31] With TNM staging, the cancer is classified based on the size of the primary tumor and whether it has invaded adjacent structures (T), spread to lymph nodes ...
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