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The UpToDate system is an evidence-based clinical resource. It includes a collection of medical and patient information, access to Lexicomp drug monographs and drug-to-drug interactions, and a number of medical calculators. UpToDate is written by over 7,100 physician authors, editors, and peer reviewers. It is available both via the Internet ...
Rose created the first version of UpToDate, in his house in 1992. It was released on floppy disks. In October 2017, more than 1.3 million clinicians in 187 countries have consulted UpToDate's website and mobile apps, with viewings of more than 32 million topics per month. [5]
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Using another interface, an advanced user could edit the knowledge base to keep it up to date with new drugs. The inference engine combines the rules from the knowledge base with the patient's data. The communication mechanism allows the system to show the results to the user as well as have input into the system. [2] [1]
That is, software which can be freely used, copied, studied, modified, and redistributed by everyone that obtains a copy. Typically, this means software which is distributed with a free software license, and whose source code is available to anyone who receives a copy of the software. Free and open-source software portal
The first edition of The Merck Manual was published in 1899 by Merck & Co., Inc. for physicians and pharmacists and was titled Merck's Manual of the Materia Medica. [6] [7] The 192 page book which sold for US $1.00, was divided into three sections, Part I ("Materia Medica") was an alphabetical listing of all known compounds thought to be of therapeutic value with uses and doses; Part II ...
A PDF file is organized using ASCII characters, except for certain elements that may have binary content. The file starts with a header containing a magic number (as a readable string) and the version of the format, for example %PDF-1.7. The format is a subset of a COS ("Carousel" Object Structure) format. [23]