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Endometrial hyperplasia is a condition of excessive proliferation of the cells of the endometrium, or inner lining of the uterus. Most cases of endometrial hyperplasia result from high levels of estrogens , combined with insufficient levels of the progesterone-like hormones which ordinarily counteract estrogen's proliferative effects on this ...
An endometrial polyp or uterine polyp is a mass in the inner lining of the uterus. [1] They may have a large flat base or be attached to the uterus by an elongated pedicle (pedunculated). [2] [3] Pedunculated polyps are more common than sessile ones. [4] They range in size from a few millimeters to several centimeters. [3]
According to guidelines set by the American College of Obstetricians and Gynecologists, if a patient's endometrial stripe is 4 mm thick or less, endometrial cancer can usually be ruled out.
Uterine malformations are sometimes referred to as congenital uterine anomalies. [ 28 ] [ 29 ] A uterine malformation is an abnormality in the development of a person's uterus. This condition can result in fertility problems such as increased risk of miscarriage.
(Reuters) -Merck said on Friday a combination therapy being developed with partner Eisai failed a late-stage trial testing it as a first-line treatment for a type of cancer in the uterus lining.
Endometrial intraepithelial neoplasia (EIN) is a premalignant lesion of the uterine lining that predisposes to endometrioid endometrial adenocarcinoma. It is composed of a collection of abnormal endometrial cells, arising from the glands that line the uterus , which have a tendency over time to progress to the most common form of uterine cancer ...
The initial treatment for endometrial cancer is surgery; 90% of women with endometrial cancer are treated with some form of surgery. [23] Surgical treatment typically consists of hysterectomy including a bilateral salpingo-oophorectomy , which is the removal of the uterus, and both ovaries and Fallopian tubes.
There are a number of indications for obtaining an endometrial biopsy from a non-pregnant woman: [citation needed]. Women with chronic anovulation such as the polycystic ovary syndrome are at increased risk for endometrial problems and an endometrial biopsy may be useful to assess their lining specifically to rule out endometrial hyperplasia or cancer.