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Protein tyrosine phosphatase non-receptor type 5 is an enzyme that in humans is encoded by the PTPN5 gene. [5] [6]Protein tyrosine phosphatase (), non-receptor type 5, also known as STEP (STriatal-Enriched protein tyrosine Phosphatase), was the first brain-specific PTP discovered. [5]
Ser/Thr and Tyr dual-specificity phosphatases are a group of enzymes with both Ser/Thr (EC 3.1.3.16) and tyrosine-specific protein phosphatase (EC 3.1.3.48) activity able to remove the serine/threonine or the tyrosine-bound phosphate group from a wide range of phosphoproteins, including a number of enzymes that have been phosphorylated under ...
Tyrosine-protein phosphatase non-receptor type 6, also known as Src homology region 2 domain-containing phosphatase-1 (SHP-1), is an enzyme that in humans is encoded by the PTPN6 gene. [ 5 ] Function
Receptor-type tyrosine-protein phosphatase T is an enzyme that in humans is encoded by the PTPRT gene. [ 5 ] [ 6 ] [ 7 ] PTPRT is also known as PTPrho, PTPρ and human accelerated region 9.
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.
Tumorigenesis is enhanced by abnormal proliferation of immature thymocytes due to low levels of Lck. [20] Lymphoid protein tyrosine phosphatase (lyp), is one of the suppressor of lck activity and mutations in this protein are correlated with the onset of diabetes 1. Increased activity of lck promote the onset of the diabetes 1.
Tyrosine-protein phosphatase non-receptor type 13 is an enzyme that in humans is encoded by the PTPN13 gene. [ 5 ] [ 6 ] The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family.
Protein tyrosine phosphatase non-receptor type 22 (PTPN22) is a cytoplasmatic protein encoded by gene PTPN22 and a member of PEST family of protein tyrosine phosphatases. This protein is also called "PEST-domain Enriched Phosphatase" ("PEP") or "Lymphoid phosphatase" ("LYP").