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In United States Pharmacopeia (USP) General Chapter <711> Dissolution, there are four dissolution apparatuses standardized and specified. [6] They are: USP Dissolution Apparatus 1 – Basket (37 °C ± 0.5 °C ) USP Dissolution Apparatus 2 – Paddle (37 °C ± 0.5 °C) USP Dissolution Apparatus 3 – Reciprocating Cylinder (37 °C ± 0.5 °C)
The solubility classification is based on a United States Pharmacopoeia (USP) aperture. The intestinal permeability classification is based on a comparison to the intravenous injection. All those factors are highly important because 85% of the most sold drugs in the United States and Europe are orally administered. [citation needed]
I think it would make the article clearer if "dissolution" was explained. CBHA 03:22, 10 May 2013 (UTC) [] @CBHA: A good suggestion but I disagree. Dissolution testing is a common name used in the Pharma industry, it should be pretty self-evident to most readers what dissolution means even if your not sure or don't work in that field ( a simple Google search can rectify any doubts).
The USP is published in a combined volume with the National Formulary (a formulary) as the USP-NF. [2] If a drug ingredient or drug product has an applicable USP quality standard (in the form of a USP-NF monograph), it must conform in order to use the designation "USP" or "NF".
A Soxhlet extractor is a piece of laboratory apparatus [1] invented in 1879 by Franz von Soxhlet. [2] It was originally designed for the extraction of a lipid from a solid material. Typically, Soxhlet extraction is used when the desired compound has a limited solubility in a solvent, and the impurity is insoluble in that solvent. It allows for ...
A federal jury in Nevada has awarded more than $34 million to a woman who was arrested at age 18, wrongly convicted twice, and served nearly 16 years in a Nevada state prison for a 2001 killing ...
In pharmaceutics, sink condition is a term mostly related to the dissolution testing procedure.. It means using a sheer volume of solvent, usually about 5 to 10 times greater than the volume present in the saturated solution of the targeted chemical (often the API, and sometimes the excipients) contained in the dosage form being tested.
A suburban New York police department routinely violated residents’ civil rights, including making illegal arrests and using unnecessary strip and cavity searches, according to a new U.S ...