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Many dialysis patients have low intakes of calcium due to avoidance of foods containing phosphorus and potassium. Lack of calcium can lead to renal osteodystrophy (bone weakening). On the other hand, too much calcium can cause calcification or calciphylaxis (calcium deposits in places such as the heart. [5]
The deposits are collected in the inner medullary interstitium in the basement membranes of the thin limbs of the loop of Henle. [9] The calcium phosphate plaques can enlarge into the surrounding interstitial tissue, or even rupture into the tubule lumen and can promote calcium oxalate stone formation. [1]
Chronic kidney disease. High cholesterol. Physical inactivity. Obesity. ... Coronary calcium scan, a type of CT scan that measures calcium build-up in the arteries supplying your heart.
Calcinosis is the formation of calcium deposits in any soft tissue. [1] It is a rare condition that has many different causes. These range from infection and injury to systemic diseases like kidney failure.
Hypocalcemia (low blood calcium) and hypercalcemia (high blood calcium) are both serious medical disorders. Osteoporosis, osteomalacia and rickets are bone disorders linked to calcium metabolism disorders and effects of vitamin D. Renal osteodystrophy is a consequence of chronic kidney failure related to the calcium metabolism.
Factors involved in the development of hypercalcemia include excess intestinal absorption of calcium, saturation of the bone's buffering capacity for calcium, decreased renal excretion, and abnormal vitamin D metabolism. [3] [10] [11] Underlying kidney disease is a risk factor for MAS, but even people with healthy kidneys can develop the ...
Metastatic calcinosis cutis is the consequence of calcium salts precipitating in normal tissue due to an underlying abnormality in the metabolism of phosphate and/or calcium. [2] Metastatic calcification can result from any systemic condition raising serum calcium and/or phosphate levels. Chronic renal failure is the most frequent underlying ...
Tumoral calcinosis is a rare condition in which there is calcium deposition in the soft tissue in periarticular location, around joints, outside the joint capsule. [1] They are frequently (0.5–3%) seen in patients undergoing renal dialysis. Clinically also known as hyperphosphatemic familial tumoral calcinosis (HFTC), is often caused by ...