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  2. Clearance (pharmacology) - Wikipedia

    en.wikipedia.org/wiki/Clearance_(pharmacology)

    K is the clearance [mL/min] or [m 3 /s] C is the concentration [mmol/L] or [mol/m 3] (in the United States often [mg/mL]) From the above definitions it follows that is the first derivative of concentration with respect to time, i.e. the change in concentration with time. It is derived from a mass balance.

  3. Cardiac output - Wikipedia

    en.wikipedia.org/wiki/Cardiac_output

    Major factors influencing cardiac output – heart rate and stroke volume, both of which are variable. [1]In cardiac physiology, cardiac output (CO), also known as heart output and often denoted by the symbols , ˙, or ˙, [2] is the volumetric flow rate of the heart's pumping output: that is, the volume of blood being pumped by a single ventricle of the heart, per unit time (usually measured ...

  4. Fick principle - Wikipedia

    en.wikipedia.org/wiki/Fick_principle

    Assuming a hemoglobin concentration of 15 g/dL and an oxygen saturation of 99%, the oxygen concentration of arterial blood is approximately 200 mL of O 2 per L. The saturation of mixed venous blood is approximately 75% in health. Using this value in the above equation, the oxygen concentration of mixed venous blood is approximately 150 mL of O ...

  5. Metabolic equivalent of task - Wikipedia

    en.wikipedia.org/wiki/Metabolic_equivalent_of_task

    The metabolic equivalent of task (MET) is the objective measure of the ratio of the rate at which a person expends energy, relative to the mass of that person, while performing some specific physical activity compared to a reference, currently set by convention at an absolute 3.5 mL of oxygen per kg per minute, which is the energy expended when sitting quietly by a reference individual, chosen ...

  6. Assessment of kidney function - Wikipedia

    en.wikipedia.org/wiki/Assessment_of_kidney_function

    The above formula only applies for GFR calculation when it is equal to the clearance rate. The normal range of GFR, adjusted for body surface area, is 100–130 average 125 (mL/min)/(1.73 m 2) in men and 90–120 (mL/min)/(1.73 m 2) in women younger than the age of 40.

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  8. Plasma renin activity - Wikipedia

    en.wikipedia.org/wiki/Plasma_renin_activity

    Reference ranges for blood tests of plasma renin activity can be given both in mass and in international units (μIU/mL or equivalently mIU/L, improperly shown as μU/mL or U/L, confusing mcU/mL used where Greek μ not available), with the former being roughly convertible to the latter by multiplying with 11.2. [3]

  9. Bruce protocol - Wikipedia

    en.wikipedia.org/wiki/Bruce_protocol

    [citation needed] The heart rate formula most often used for the Bruce is the Karvonen formula (below). A more accurate formula, offered in a study published in the journal, Medicine & Science in Sports & Exercise, is 206.9 - (0.67 x age) which can also be used to more accurately determine VO2 Max, but may produce significantly different results.