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Cariprazine, sold under the brand name Vraylar among others, is an atypical antipsychotic developed by Gedeon Richter, [8] which is used in the treatment of schizophrenia and bipolar disorder. [9] It is also prescribed as an add-on treatment for bipolar depression [ 10 ] and major depressive disorder . [ 6 ]
Prucalopride, sold under brand names Resolor and Motegrity among others, is a medication acting as a selective, high affinity 5-HT 4 receptor agonist [4] which targets the impaired motility associated with chronic constipation, thus normalizing bowel movements.
Constipation occurs when bowel movements become difficult or infrequent. Usually, constipation is classified as fewer than three bowel movements a week, according to Cleveland Clinic .
Certain medications can also affect your bowel movements, including some antidepressants, iron supplements, opioids (something to be keep in mind after you’ve had surgery) and GLP-1 medications ...
They are used to treat certain gastrointestinal symptoms, including abdominal discomfort, bloating, constipation, heart burn, nausea, and vomiting; and certain gastrointestinal disorders, including irritable bowel syndrome, gastritis, [2] gastroparesis, and functional dyspepsia.
In standard medicine, the most frequent uses of enemas are to relieve constipation and for bowel cleansing before a medical examination or procedure; [5] also, they are employed as a lower gastrointestinal series (also called a barium enema), [6] to treat traveler's diarrhea, [7] as a vehicle for the administration of food, water or medicine ...
If possible, alternate medications should be prescribed that avoid the side effect of constipation. [citation needed] Given that all opioids can cause constipation, [6] it is recommended that any patient placed on opioid pain medications be given medications to prevent constipation before it occurs. Daily medications can also be used to promote ...
As with illicit psychoactive drugs in general, risks connected to rectal administration stem from the often unknown purity and composition of the drugs. This leads to the user not knowing if and what substances, by-products or cutting agents are present in their drugs [11] before administering them rectally. Possible impurities or falsely ...
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