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Hydroxychloroquine and chloroquine have numerous, potentially serious, side effects, such as retinopathy, hypoglycemia, or life-threatening arrhythmia and cardiomyopathy. [26] Both drugs have extensive interactions with prescription drugs, affecting the therapeutic dose and disease mitigation. [26] [27] Some people have allergic reactions to ...
Hydroxychloroquine increases [40] lysosomal pH in antigen-presenting cells [19] by two mechanisms: As a weak base, it is a proton acceptor and via this chemical interaction, its accumulation in lysozymes raises the intralysosomal pH, but this mechanism does not fully account for the effect of hydroxychloroquine on pH.
Serious side effects include problems with vision, muscle damage, seizures, and low blood cell levels. [ 1 ] [ 4 ] Chloroquine is a member of the drug class 4-aminoquinoline . [ 1 ] As an antimalarial, it works against the asexual form of the malaria parasite in the stage of its life cycle within the red blood cell . [ 1 ]
For a time, it was hoped that hydroxychloroquine sulfate and chloroquine, drugs commonly used to treat lupus, rheumatoid arthritis (RA), and malaria, would be key weapons in the fight against ...
Dr. John Torres discussed the side effects of hydroxychloroquine, which doesn't have any proven benefits as a treatment for the coronavirus. Trump says he's taking hydroxychloroquine to prevent ...
Combinations of DMARDs are often used, because each drug in the combination can be used in a smaller dose than if it were given alone, thus reducing the risk of side effects. [citation needed] Many patients receive an NSAID and at least one DMARD, sometimes with low-dose oral glucocorticoids. If disease remission is observed, regular NSAIDs or ...
When prescribed by a doctor and carefully monitored, testosterone is relatively safe for women and side effects are rare, experts said. When men start testosterone therapy, it is typically given ...
In women with insulin resistance, such as those with polycystic ovary syndrome, androgen levels are often elevated. [184] Metformin, an insulin-sensitizing medication, has indirect antiandrogenic effects in such women, decreasing testosterone levels by as much as 50% secondary to its beneficial effects on insulin sensitivity. [184] [185] [186]