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Atrial septal defect (ASD) is a congenital heart defect in which blood flows between the atria (upper chambers) of the heart.Some flow is a normal condition both pre-birth and immediately post-birth via the foramen ovale; however, when this does not naturally close after birth it is referred to as a patent (open) foramen ovale (PFO).
Defective embryonic formation of the heart results in multiple holes between the heart chambers. In AVSD, all four chambers are connected, but the exact characteristics of holes and malformations may vary between patients. Even within the categories of "complete" and "partial" AVSD, multiple morphologies exist, with varying clinical consequences.
Almost immediately after the infant is born, the foramen ovale and ductus arteriosus close. The major changes that are made by the body occur at the first breath (in the case of heart and lung functions) and up to weeks after birth (such as the liver's enzyme synthesis). The foramen ovale becomes the fossa ovalis as the foramen closes while ...
The most common problems with an opening found in the heart with Lutembacher's syndrome is Ostium Secundum. Ostium Secundum is a hole that is found within the flap of tissue (septum primum) that will eventually close the hole between the two atria after birth.
Since some people with congenital heart disease have a lower quality of life that is related to their condition, some people may struggle with finding a job, engaging in physical exercise, with their fertility, and clinical depression as examples. An estimated 31% of adults with congenital heart disease also have mood disorders. [51]
An atrial septal defect is a hole in the septum that divides the right and left atria (the upper two chambers) of the heart. In the heart of a developing fetus, there are several holes between the atria, however these are expected to close before birth. This congenital condition arises if one of these holes remains. [6]
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A VSD can cause a left-to-right shunt of blood flow in the heart and is one of the most common of the congenital heart defects. This type of shunt is an acyanotic disorder that can result in ventricular hypertrophy. [4] The alignment of interventricular septum and interatrial septum is disturbed in various congenital heart diseases. [5]
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