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Grail says the Galleri test can indicate where the tumor originated from with 88% accuracy thanks to DNA fragments unique to specific cancers. “That tells you where to start looking,” says Volk.
The blood test, called Galleri, can detect multiple types of cancer early and targets 80% of cancers currently not screened for that result in cancer deaths, Grail CEO Bob Ragu
Despite Grail promoting the test as a "groundbreaking and potentially life-saving advance", the results of early trials were poor. [5] A subsequent large-scale NHS England trial has been described by experts as overhyped and unethical. Grail is facing discontent and legal action from investors who suspect that its cancer testing claims misled them.
The objective of cancer screening is to detect cancer before symptoms appear, involving various methods such as blood tests, urine tests, DNA tests, and medical imaging. [ 1 ] [ 2 ] The purpose of screening is early cancer detection, to make the cancer easier to treat and extending life expectancy. [ 3 ]
In 2018 data from Grail's first clinical trial for the Galleri test, the Circulating Cell-free Genome Atlas Study, [5] the test detected 87% of late-stage cancers and 38% of early-stage cancers. [6] The test does not diagnose cancer; [7] rather, it detects possible signs of cancer in order to help direct follow-up diagnostic testing. [8]
Reuters reported on Tuesday that Illumina is expected to get an order from EU antitrust later this week to sell Grail, which develops blood-based early cancer detection tests.
The following is a list of cancer types. Cancer is a group of diseases that involve abnormal increases in the number of cells, with the potential to invade or spread to other parts of the body. [1] Not all tumors or lumps are cancerous; benign tumors are not classified as being cancer because they do not spread to other parts of the body. [1]
Grail, valued at $7.1 billion under Illumina's deal, is seeking to market a blood test that can diagnose many kinds of cancer, known as a liquid biopsy. Illumina had spun off Grail in 2016 but ...