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Elongation factors are a set of proteins that function at the ribosome, during protein synthesis, to facilitate translational elongation from the formation of the first to the last peptide bond of a growing polypeptide. Most common elongation factors in prokaryotes are EF-Tu, EF-Ts, EF-G. [1]
Elongation factor 1-alpha 1 (eEF1a1) is a translation elongation protein, expressed across eukaryotes. In humans, it is encoded by the EEF1A1 gene. [5] [6] This gene encodes an isoform of the alpha subunit of the elongation factor-1 complex, which is responsible for the enzymatic delivery of aminoacyl tRNAs to the ribosome. This isoform (alpha ...
13629 Ensembl ENSG00000167658 ENSMUSG00000034994 UniProt P13639 P58252 RefSeq (mRNA) NM_001961 NM_007907 RefSeq (protein) NP_001952 NP_031933 Location (UCSC) Chr 19: 3.98 – 3.99 Mb Chr 10: 81.01 – 81.02 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Eukaryotic elongation factor 2 is a protein that in humans is encoded by the EEF2 gene. It is the archaeal and eukaryotic ...
The elongation and membrane targeting stages of eukaryotic translation. The ribosome is green and yellow, the tRNAs are dark-blue, and the other proteins involved are light-blue. Elongation depends on eukaryotic elongation factors. At the end of the initiation step, the mRNA is positioned so that the next codon can be translated during the ...
Various species of green algae, red algae, chromalveolates, and fungi lack the EF-1α gene but instead possess a related gene called EFL (elongation factor-like). Although its function has not been studied in depth, it appears to be similar to EF-1α.
1 Function. 2 Interactions. ... EEF1B, EEF1B1, EF1B, eukaryotic translation elongation factor 1 beta 2: ... Elongation factor 1-beta is a protein that in humans is ...
13628 Ensembl ENSG00000101210 ENSMUSG00000016349 UniProt Q05639 P62631 RefSeq (mRNA) NM_001958 NM_007906 RefSeq (protein) NP_001949 NP_031932 Location (UCSC) Chr 20: 63.49 – 63.5 Mb Chr 2: 180.79 – 180.8 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Elongation factor 1-alpha 2 is a protein that in humans is encoded by the EEF1A2 gene. Function This gene encodes an isoform of ...
Eukaryotic elongation factor-2 kinase (eEF-2 kinase or eEF-2K), also known as calmodulin-dependent protein kinase III (CAMKIII) and calcium/calmodulin-dependent eukaryotic elongation factor 2 kinase, [5] is an enzyme that in humans is encoded by the EEF2K gene.