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Aloe emodin (1,8-dihydroxy-3-(hydroxymethyl)anthraquinone) is an anthraquinone and an isomer of emodin present in aloe latex, an exudate from the aloe plant. It has a strong stimulant-laxative action. [1] Aloe emodin is not carcinogenic when applied to the skin, although it may increase the carcinogenicity of some kinds of radiation. [2] [3]
Foslevodopa is a medication which acts as a prodrug for levodopa, originally invented in the 1980s but not developed for medical use at that time. [1] It is approved for use in a subcutaneous infusion as a fixed-dose combination with foscarbidopa for the treatment of Parkinson's disease , under the brand name Vyalev .
Retinyl palmitate, or vitamin A palmitate, is the ester of retinol and palmitic acid, with formula C 36 H 60 O 2.It is the most abundant form of vitamin A storage in animals. [2]
The SKh-1 utility transport was designed by Anatolii Georgievich Bedunkovich as a multi-purpose utility transport biplane of mixed construction with wooden folding wings, fitted with slotted ailerons and flaps on all four trailing edges, a welded mild steel tubing fuselage and wooden tail-section with fabric covering.
[1] [2] The first recorded knockout mouse was created by Mario R. Capecchi, Martin Evans, and Oliver Smithies in 1989, for which they were awarded the 2007 Nobel Prize in Physiology or Medicine. Aspects of the technology for generating knockout mice, and the mice themselves have been patented in many countries by private companies.
SHIRPA is a standardized set of experimental procedures used by scientists to characterize the phenotype of genetically modified laboratory mice. The protocols are designed to test muscle function, cerebellar function, sensory function and neuropsychiatric function. [1]
Humanized mice are commonly used as small animal models in biological and medical research for human therapeutics. [ 2 ] A humanized mouse or a humanized mouse model is one that has been xenotransplanted with human cells and/or engineered to express human gene products, so as to be utilized for gaining relevant insights in the in vivo context ...
[1] Currently, rodents are commonly used in animal testing, particularly mice and rats, but also guinea pigs, hamsters, gerbils and others. Mice are the most commonly used vertebrate species, due to their availability, size, low cost, ease of handling, and fast reproduction rate .