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  2. Mucin-16 - Wikipedia

    en.wikipedia.org/wiki/Mucin-16

    CA-125 was initially detected using the murine monoclonal antibody designated OC125. Robert Bast, Robert Knapp and their research team first isolated this monoclonal antibody in 1981. [28] The protein was named "cancer antigen 125" because OC125 was the 125th antibody produced against the ovarian cancer cell line that was being studied. [29]

  3. Tumor marker - Wikipedia

    en.wikipedia.org/wiki/Tumor_marker

    Reflect the stage of cancer; By determining the stage of cancer, it's possible to give a prognosis and treatment plan. [4] Screening for cancers; No screening test is wholly specific, and a high level of tumor marker can still be found in benign tumors. The only tumor marker currently used in screening is PSA (prostate-specific antigen ...

  4. Cancer biomarker - Wikipedia

    en.wikipedia.org/wiki/Cancer_biomarker

    The Oncotype DX® breast cancer assay is one such test used to predict the likelihood of breast cancer recurrence. This test is intended for women with early-stage (Stage I or II), node-negative, estrogen receptor -positive (ER+) invasive breast cancer who will be treated with hormone therapy .

  5. This blood test screens for 50 different types of cancer. Is ...

    www.aol.com/lifestyle/blood-test-screens-50...

    For about 1% of those ages 50 to 79, test results will show a cancer signal was detected, along with the organ or tissue type associated with that specific cancer signal. An estimated 40% of these ...

  6. Tumor antigen - Wikipedia

    en.wikipedia.org/wiki/Tumor_antigen

    Tumor antigen is an antigenic substance produced in tumor cells, i.e., it triggers an immune response in the host. Tumor antigens are useful tumor markers in identifying tumor cells with diagnostic tests and are potential candidates for use in cancer therapy .

  7. Ovarian cancer - Wikipedia

    en.wikipedia.org/wiki/Ovarian_cancer

    However, treatment based only on elevated CA-125 levels and not any symptoms can increase side effects without any prolongation of life, so the implication of the outcome of a CA-125 test can be discussed before taking it. [122] The recommendation as of 2014 is recurrent cancer may be present if the CA-125 level is twice normal. [28]

  8. Cancer/testis antigens - Wikipedia

    en.wikipedia.org/wiki/Cancer/testis_antigens

    Cancer/testis (CT) antigens are a group of proteins united by their importance in development and in cancer immunotherapy. In general, expression of these proteins is restricted to male germ cells in the adult animal. However, in cancer these developmental antigens are often re-expressed and can serve as a locus of immune activation.

  9. Ovarian germ cell tumors - Wikipedia

    en.wikipedia.org/wiki/Ovarian_Germ_Cell_Tumors

    Lactate dehydrogenase, alkaline phosphatase and cancer antigen 125 might potentially increase as well. [24] To visualize the location and morphology of the tumor, transvaginal ultrasonography is usually employed. [1] The most characteristic appearance is a parenchymal-like heteroechoic mass with sharp borders and high vascularization. [1]

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