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Pneumocystis pneumonia (PCP), also known as Pneumocystis jirovecii pneumonia (PJP), is a form of pneumonia that is caused by the yeast-like fungus Pneumocystis jirovecii. [ 3 ] [ 4 ] Pneumocystis specimens are commonly found in the lungs of healthy people although it is usually not a cause for disease. [ 5 ]
Pneumocystis jirovecii (previously P. carinii) is a yeast-like fungus of the genus Pneumocystis. The causative organism of Pneumocystis pneumonia , it is an important human pathogen , particularly among immunocompromised hosts .
Pneumocystosis is a fungal infection that most often presents as Pneumocystis pneumonia in people with HIV/AIDS or poor immunity. [1] [7] It usually causes cough, difficulty breathing and fever, and can lead to respiratory failure. [4]
Fungal pneumonia is an infection of the lungs by fungi. It can be caused by either endemic or opportunistic fungi or a combination of both. Case mortality in fungal pneumonias can be as high as 90% in immunocompromised patients, [1] [2] though immunocompetent patients generally respond well to anti-fungal therapy.
[1] [7] Systemic fungal infections are more serious and include cryptococcosis, histoplasmosis, pneumocystis pneumonia, aspergillosis and mucormycosis. [3] Signs and symptoms range widely. [3] There is usually a rash with superficial infection. [2] Fungal infection within the skin or under the skin may present with a lump and skin changes. [3]
Pneumocystis murina is unique for several reasons. Firstly, it is only found in laboratory mice, not in natural environments. [7] Secondly, it is a pathogen that causes cyst formation in the respiratory tract of immunocompromised lab mice, leading to clinical signs of infection such as dyspnea, weight loss, hunched posture, and scaly skin. [6]
Primaquine is a medication used to treat and prevent malaria and to treat Pneumocystis pneumonia. [2] Specifically it is used for malaria due to Plasmodium vivax and Plasmodium ovale along with other medications and for prevention if other options cannot be used. [2] It is an alternative treatment for Pneumocystis pneumonia together with ...
An opportunistic infection is an infection caused by pathogens (bacteria, fungi, parasites or viruses) that take advantage of an opportunity not normally available.These opportunities can stem from a variety of sources, such as a weakened immune system (as can occur in acquired immunodeficiency syndrome or when being treated with immunosuppressive drugs, as in cancer treatment), [1] an altered ...