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Other severe side effects include unusual or severe tiredness or weakness, as well as yellowing of the skin or the eyes. [41] When baclofen is administered intrathecally, it may cause CNS depression accompanied with cardiovascular collapse and respiratory failure. Tizanidine may lower blood pressure. This effect can be controlled by ...
Baclofen, sold under the brand name Lioresal among others, is a medication used to treat muscle spasticity, such as from a spinal cord injury or multiple sclerosis. [8] [9] It may also be used for hiccups and muscle spasms near the end of life, [9] and off-label to treat alcohol use disorder [10] [11] or opioid withdrawal symptoms. [12]
Another class of antispasmodics for such treatment includes cyclobenzaprine, carisoprodol, diazepam, orphenadrine, and tizanidine. [7] Meprobamate is another effective antispasmodic which was first introduced for clinical usage in 1955 mainly as an anxiolytic and soon afterward became a blockbuster psychotropic drug.
However, nonbenzodiazepine (including cyclobenzaprine) treatment was found to have a lower risk of medication abuse and continuation of use against medical advice. [medical citation needed] Side effects such as sedation and ataxia are also less pronounced with nonbenzodiazepine antispasmodics. [medical citation needed]
Natalizumab is considered highly effective in terms of relapse rate reduction and halting disability progression, however, it is considered a second-line treatment because of the risk of adverse side-effects. [36] Natalizumab halves the risk of relapsing when compared to interferons, having an overall efficacy of over 70%. [36]
Anticholinergics generally have antisialagogue effects (decreasing saliva production), and most produce some level of sedation, both being advantageous in surgical procedures. [8] [9] Until the beginning of the 20th century, anticholinergic drugs were widely used to treat psychiatric disorders. [10]
Some patients request to be switched to a different narcotic due to stigma associated with a particular drug (e.g. a patient refusing methadone due to its association with opioid addiction treatment). [4] Equianalgesic charts are also used when calculating an equivalent dosage of the same drug, but with a different route of administration.
Eperisone (formulated as the eperisone hydrochloride salt) is an antispasmodic drug.. Eperisone acts by relaxing both skeletal muscles and vascular smooth muscles, and demonstrates a variety of effects such as reduction of myotonia, improvement of circulation, and suppression of the pain reflex.
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related to: baclofen vs cyclobenzaprine baclofen side effects at beginning dosage treatment- 109 S High St #100, Columbus, OH · Directions · (614) 224-4261
The lowest prices on specific drugs - Family Circle