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Melittin is the main compound in bee venom, accounting for the potential lethality of a bee sting, which causes an anaphylactic reaction in some people. [5] At the sites of multiple stings, localized pain, swelling, and skin redness occur, and if bees are swallowed, life-threatening swelling of the throat and respiratory passages may develop. [5]
Apitoxin or bee venom is the venom produced by the honey bee. It is a cytotoxic and hemotoxic bitter colorless liquid containing proteins , which may produce local inflammation . It may have similarities to sea nettle toxin .
MCD peptide is a component of bumblebee (Megabombus pennsylvanicus) venom. [2] In addition to MCD peptide, melittin and apamin have also been identified in this venom and are also described as voltage-dependent channel blockers. MCD peptide is also present in the venom of the honey bee Apis mellifera. [3]
Apamin was first isolated by Habermann in 1965 from Apis mellifera, the Western honey bee. Apamin was named after this bee. Bee venom contains many other compounds, like histamine, phospholipase A2, hyaluronidase, MCD peptide, and the main active component melittin. Apamin was separated from the other compounds by gel filtration and ion ...
Apitherapy is the medical use of honeybee products such as honey, pollen, bee bread, propolis, royal jelly and bee venom. One of the major peptides in bee venom, called Melittin, has the potential to treat inflammation in people who have Rheumatoid arthritis or Multiple sclerosis. Melittin blocks the expression of inflammatory genes, thus ...
This is an accepted version of this page This is the latest accepted revision, reviewed on 21 January 2025. Colonial flying insect of genus Apis For other uses, see Honey bee (disambiguation). Honey bee Temporal range: Oligocene–Recent Pre๊ ๊ O S D C P T J K Pg N Western honey bee on the bars of a horizontal top-bar hive Scientific classification Domain: Eukaryota Kingdom: Animalia ...
The main component of bee venom responsible for pain in vertebrates is the toxin melittin; histamine and other biogenic amines may also contribute to pain and itching. [8] In one of the alternative medical uses of honey bee products, apitherapy, bee venom has been used to treat arthritis and other painful conditions. [9]
Bee showing its proboscis. The introduction of certain chemical substances—such as ethanol or pesticides or defensive toxic biochemicals produced by plants—to a bee's environment can cause the bee to display abnormal or unusual behavior and disorientation. In sufficient quantities, such chemicals can poison and even kill the bee.