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  2. Melatonin as a medication and supplement - Wikipedia

    en.wikipedia.org/wiki/Melatonin_as_a_medication...

    Melatonin is thought to activate melatonin receptors in the suprachiasmatic nucleus of the hypothalamus to regulate the circadian clock and sleep–wake cycles. [21] When used several hours before sleep according to the phase response curve for melatonin in humans, small amounts (0.3 mg [ 56 ] ) of melatonin shift the circadian clock earlier ...

  3. Non-24-hour sleep–wake disorder - Wikipedia

    en.wikipedia.org/wiki/Non-24-hour_sleep–wake...

    Then, using endogenous melatonin as a marker for circadian rhythms, several research groups showed that appropriately timed melatonin administration could entrain free-running rhythms in the totally blind: they found that 6 out of 7 patients treated with 10 mg melatonin at bedtime were normally entrained, and when the dose was gradually reduced ...

  4. Delayed sleep phase disorder - Wikipedia

    en.wikipedia.org/wiki/Delayed_sleep_phase_disorder

    Side effects of melatonin may include sleep disturbance, nightmares, daytime sleepiness, and depression, though the current tendency to use lower doses has decreased such complaints. Large doses of melatonin can even be counterproductive: Lewy et al. [ 48 ] provide support to "the idea that too much melatonin may spill over onto the wrong zone ...

  5. Rapid eye movement sleep behavior disorder - Wikipedia

    en.wikipedia.org/wiki/Rapid_eye_movement_sleep...

    Melatonin and clonazepam are the most frequently used, [2] and are comparably effective, [24] but melatonin offers a safer alternative, because clonazepam can produce undesirable side effects. [17] Medications that may worsen RBD and should be stopped if possible are tramadol, mirtazapine, antidepressants, and beta blockers. [2]

  6. Ramelteon - Wikipedia

    en.wikipedia.org/wiki/Ramelteon

    Side effects of ramelteon include somnolence, dizziness, fatigue, nausea, exacerbated insomnia, and changes in hormone levels. [3] Ramelteon is an analogue of melatonin and is a selective agonist of the melatonin MT 1 and MT 2 receptors. [3] The half-life and duration of ramelteon are much longer than those of melatonin. [7]

  7. Why Storms Make You Sleepy: The Science Behind Pre-Storm ...

    www.aol.com/why-storms-sleepy-science-behind...

    Shifting weather patterns can also influence hormone levels, according to experts, including melatonin, the hormone that regulates sleep. Increased melatonin production during overcast or stormy ...

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