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A synovial sarcoma (also known as malignant synovioma [1]) is a rare form of cancer which occurs primarily in the extremities of the arms or legs, often in proximity to joint capsules and tendon sheaths. [2]
Pediatric rhabdomyosarcoma patients have a 50–85% long term survival rate. [23] Osteosarcoma is a cancer of the bone that is treated with surgical resection of as much of the cancer as possible, often along with chemotherapy. [24] Radiotherapy is a second alternative to surgery, although not as successful.
Kaposi sarcoma, a rare cancer of the cells that line blood vessels in the skin and mucous membranes, is caused by human herpesvirus 8. Kaposi sarcoma often occurs in patients with acquired immune deficiency syndrome. Kaposi sarcoma, however, has different characteristics from typical soft-tissue sarcomas and is treated differently. [8]
Ewing sarcoma occurs about 10- to 20-fold more commonly in people of European descent compared to people of African descent. [49] [10] Ewing sarcoma is the second most common bone cancer in children and adolescents, with poor prognosis and outcome in ~70% of initial diagnoses and 10–15% of relapses. [50]
In fact, multi-agent chemotherapy is indicated for all patients with rhabdomyosarcoma. Before the use of adjuvant and neoadjuvant therapy involving chemotherapeutic agents, treatment solely by surgical means had a survival rate of <20%. Modern survival rates with adjuvant therapy are approximately 60–70%. [8] [39]
The four year survival rate without remission for local ARMS tumors is 65 percent, while the four year survival rate with metastatic ARMS is only 15 percent. [1] Patients who have metastatic ARMS positive with PAX3-FOXO1 fusion often have a poorer outcome than patients positive with PAX7-FOXO1 fusion, with a four-year survival rate of 8 percent ...
Malignant synovioma, also known as: synovial sarcoma This page was last edited on 30 December 2019, at 06:20 (UTC). Text is available under the Creative Commons ...
It is found on the cell surface of Ewing's sarcoma tumors [15] and is positive in granulosa cell tumors. [16] It is more expressed in malignant gliomas than in the brain, and such overexpression results in higher levels of invasiveness and lower rates of survival. [17]