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About 80 percent of pancreatitis cases are caused by gallstones or alcohol. Choledocholithiasis (gallstones in the bile duct) are the single most common cause of acute pancreatitis, [12] and alcoholism is the single most common cause of chronic pancreatitis.
Acute pancreatitis (AP) is a sudden inflammation of the pancreas.Causes include a gallstone impacted in the common bile duct or the pancreatic duct, heavy alcohol use, systemic disease, trauma, elevated calcium levels, hypertriglyceridemia (with triglycerides usually being very elevated, over 1000 mg/dL), certain medications, hereditary causes and, in children, mumps.
Alcohol misuse is a leading cause of both acute pancreatitis and chronic pancreatitis. [155] [156] Alcoholic pancreatitis can result in severe abdominal pain and may progress to pancreatic cancer. [157] Chronic pancreatitis often results in intestinal malabsorption, and can result in diabetes. [158]
Chronic pancreatitis is a long-standing inflammation of the pancreas that alters the organ's normal structure and functions. [1] It can present as episodes of acute inflammation in a previously injured pancreas, or as chronic damage with persistent pain or malabsorption.
[31] [130] [131] Although drinking alcohol excessively is a major cause of chronic pancreatitis, which in turn predisposes to pancreatic cancer, chronic pancreatitis associated with alcohol consumption is less frequently a precursor for pancreatic cancer than other types of chronic pancreatitis. [132]
Chronic pancreatitis refers to the development of pancreatitis over time. It shares many similar causes, with the most common being chronic alcohol use, with other causes including recurrent acute episodes and cystic fibrosis. Abdominal pain, characteristically relieved by sitting forward or drinking alcohol, is the most common symptom.
Other conditions that may present similarly include other causes of high anion gap metabolic acidosis such as diabetic ketoacidosis, toxic alcohol ingestion, and starvation ketosis. [2] Toxic alcohol ingestion includes methanol and ethylene glycol poisoning. [6] Pancreatitis, alcoholic hepatitis, and gastritis may also result in similar ...
Excessive alcohol intake causes alcohol poisoning, characterized by unconsciousness or, ... Alcoholism is the single most common cause of chronic pancreatitis.