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Diabetes most commonly causes damage to the long nerves that supply the feet and lower legs, causing numbness, tingling and pain (diabetic polyneuropathy). Although these symptoms may also be present, the pain and weakness of proximal diabetic neuropathy often onset more quickly and affect nerves closer to the torso. [citation needed]
Statins may sometimes cause myalgia and cramps among other possible side effects. Raloxifene (Evista) is a medication associated with a high incidence of leg cramps. Additional factors, that increase the probability of these side effects, are physical exercise, age, history of cramps, and hypothyroidism .
Peripheral neuropathy may be classified according to the number and distribution of nerves affected (mononeuropathy, mononeuritis multiplex, or polyneuropathy), the type of nerve fiber predominantly affected (motor, sensory, autonomic), or the process affecting the nerves; e.g., inflammation (), compression (compression neuropathy), chemotherapy (chemotherapy-induced peripheral neuropathy).
Most shooting pains, leg cramps and charley horses are temporary. Sometimes, they signal other problems. What you need to know about leg cramps, sudden pain and when to see a doctor
Cramp fasciculation syndrome (CFS) is a rare [1] peripheral nerve hyperexcitability disorder. It is more severe than the related (and common) disorder known as benign fasciculation syndrome ; it causes fasciculations , cramps, pain, fatigue, and muscle stiffness similar to those seen in neuromyotonia (another related condition). [ 2 ]
Irritable bowel syndrome, which affects the large intestine, causes cramping, abdominal pain, bloating, and gas, and sex can make these symptoms worse. With colitis, inflammation of the colon ...
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