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Menthol may also enhance the activity of glycine receptors and negatively modulate 5-HT 3 receptors and nAChRs. [9] Menthol is widely used in dental care as a topical antibacterial agent, effective against several types of streptococci and lactobacilli. [10] Menthol also lowers blood pressure and antagonizes vasoconstriction through TRPM8 ...
Menthoxypropanediol (also known as Cooling agent 10 [tradename of Takasago]), is a synthetic derivative of menthol.While the cooling strength of 3-(l-menthoxy)propane-1,2-diol is accepted as being about 20–25% that of menthol, it is also noted that "in a Vaseline ointment, 3-(l-menthoxy)propane-1,2-diol shows a cool feeling 2.0 to 2.5 times stronger than that of l-menthol".
Thus, the two substrates of this enzyme are (−)-menthol and NADP +, whereas its 3 products are (−)-menthone, NADPH, and H +. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD + or NADP + as acceptor. The systematic name of this enzyme class is (−)-menthol:NADP ...
[15] [16] Menthol, hinokitiol and thymol are also used in oral hygiene products. Thymol also has antiseptic and disinfectant properties. [17] Volatile monoterpenes produced by plants can attract or repel insects, thus some of them are used in insect repellents, such as citronellol, eucalyptol, limonene, linalool, hinokitiol, menthol and thymol ...
p-Menthane-3,8-diol, also known as para-menthane-3,8-diol, PMD, or menthoglycol, is an organic compound classified as a diol and a terpenoid.It is colorless. Its name reflects the hydrocarbon backbone, which is that of p-menthane.
Menthone was first synthesized by oxidation of menthol in 1881, [6] [needs update] [7] before being found as a component in essential oils in 1891. [ citation needed ] Of the isomers possible for this chemical structure (see below), the one termed l -menthone —formally, the (2 S ,5 R )- trans -2-isopropyl-5-methylcyclohexanone (see infobox ...
Chiral auxiliaries are incorporated into synthetic routes to control the absolute configuration of stereogenic centers. David A. Evans' synthesis of the macrolide cytovaricin, considered a classic, utilizes oxazolidinone chiral auxiliaries for one asymmetric alkylation reaction and four asymmetric aldol reactions, setting the absolute stereochemistry of nine stereocenters.
The 4 substrates of this enzyme are (−)-menthol, NADPH, H +, and O 2, whereas its 3 products are p-menthane-3,8-diol, NADP +, and H 2 O. This enzyme belongs to the family of oxidoreductases , specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen.