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  2. Metolazone - Wikipedia

    en.wikipedia.org/wiki/Metolazone

    Metolazone may be combined with other diuretics (typically loop diuretics) to treat diuretic resistance in congestive heart failure, chronic kidney disease, and nephrotic syndrome. [3] Metolazone and a loop diuretic will synergistically enhance diuresis over the use of either agent alone.

  3. Potassium-sparing diuretic - Wikipedia

    en.wikipedia.org/wiki/Potassium-sparing_diuretic

    Structural formula of the potassium-sparing diuretics. Click to enlarge. Potassium-sparing diuretics or antikaliuretics [1] refer to drugs that cause diuresis without causing potassium loss in the urine. [2] They are typically used as an adjunct in management of hypertension, cirrhosis, and congestive heart failure. [3]

  4. Loop diuretic - Wikipedia

    en.wikipedia.org/wiki/Loop_diuretic

    Loop diuretics are principally used in the following indications: Heart failure - Giving 2.5 times of previous oral dose twice daily for those with acute decompensated heart failure is a reasonable strategy. However, daily assessment of clinical response is needed to adjust the subsequent doses. [6]

  5. Semaglutide may improve heart failure symptoms, reduce need ...

    www.aol.com/semaglutide-may-improve-heart...

    New research reports that semaglutide reduces the need and dose of loop diuretics in people with heart failure with preserved ejection fraction (HFpEF). The findings show semaglutide also improved ...

  6. Chlortalidone - Wikipedia

    en.wikipedia.org/wiki/Chlortalidone

    Chlortalidone, also known as chlorthalidone, is a thiazide-like diuretic drug [1] used to treat high blood pressure, swelling (such as occurs in heart failure, liver failure, and nephrotic syndrome), diabetes insipidus, and renal tubular acidosis.

  7. Mineralocorticoid receptor antagonist - Wikipedia

    en.wikipedia.org/wiki/Mineralocorticoid_receptor...

    A mineralocorticoid receptor antagonist (MRA or MCRA) [1] or aldosterone antagonist, is a diuretic drug which antagonizes the action of aldosterone at mineralocorticoid receptors. This group of drugs is often used as adjunctive therapy, in combination with other drugs, for the management of chronic heart failure.

  8. Heart failure - Wikipedia

    en.wikipedia.org/wiki/Heart_failure

    Heart failure is not the same as cardiac arrest, in which blood flow stops completely due to the failure of the heart to pump. [12] [13] Diagnosis is based on symptoms, physical findings, and echocardiography. [6] Blood tests, and a chest x-ray may be useful to determine the underlying cause. [14] Treatment depends on severity and case. [15]

  9. Syndrome of inappropriate antidiuretic hormone secretion

    en.wikipedia.org/wiki/Syndrome_of_inappropriate...

    He observed that sulfanilamide increased excretion of sodium in patients with heart failure. This observation was the basis for the discovery and development of modern diuretic drugs. Frederic Bartter (1914–1983) worked on hormones affecting the kidney that led to the discovery of syndrome of inappropriate antidiuretic hormone (SIADH) in 1957 ...

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