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Leprosy, also known as Hansen's disease (HD), is a long-term infection by the bacteria Mycobacterium leprae or Mycobacterium lepromatosis. [4] [7] Infection can lead to damage of the nerves, respiratory tract, skin, and eyes. [4]
Treatment of tuberculoid leprosy is continued for at least 1 to 2 years, while patients with lepromatous leprosy are generally treated for 5 years. In addition to chemotherapy , patients with leprosy need psychosocial support, rehabilitation, and surgical repair of any disfiguration.
Mycobacterium leprae has a narrow host range and apart from humans the only other hosts are nine-banded armadillos and red squirrels, [5] and armadillos have been implicated as a source of zoonotic leprosy in humans. [13] In the laboratory, mice can be infected and this is a useful animal model. [14]
Early diagnosis and treatment prevents nerve involvement, the hallmark of Hansen's disease (leprosy), and the disability it causes. Without nerve involvement, Hansen's disease (leprosy) would be a ...
Even though leprosy has ancient roots, doctors still don’t know how leprosy spreads between people. What they do know is that leprosy doesn’t spread easily and is easy to treat if detected ...
“Leprosy is classified as a neglected tropical disease, but people should know that it can hit closer to home,” says Mark Cameron, Ph.D., an associate professor and systems biologist at Case ...
Dapsone is commonly used in combination with rifampicin and clofazimine for the treatment of leprosy. [3] It is also used to both treat and prevent pneumocystis pneumonia (PCP). [3] [9] It is also used for toxoplasmosis in people unable to tolerate trimethoprim with sulfamethoxazole. [9] Dapsone by mouth was one of the first medications used to ...
The primary use of clofazimine is for the treatment of leprosy. [1] Other uses have not been proven to be safe or effective. [1]It has been studied in combination with other antimycobacterial drugs to treat Mycobacterium avium infections in people with HIV/AIDS and Mycobacterium avium paratuberculosis.