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Common side effects when used orally include itchiness and rash. [7] Common side effects when used by injection include vomiting and kidney problems. [7] While not recommended historically, starting allopurinol during an attack of gout appears to be safe. [8] [9] In those already on the medication, it should be continued even during an acute ...
Levels that cannot be brought below 6.0 mg/dL while attacks continue indicates refractory gout. [68] While historically it is not recommended to start allopurinol during an acute attack of gout, this practice appears acceptable. [69] Allopurinol blocks uric acid production, and is the most commonly used agent. [20]
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If you have frequent gout flares, gout associated with tophi, or joint damage, your provider may prescribe medication to lower uric acid levels. These can help prevent gout flares and further ...
Febuxostat, sold under the brand name Uloric among others, is a medication used long-term to treat gout due to high uric acid levels. [7] It is generally recommended only for people who cannot take allopurinol. [8] [9] It is taken by mouth. [7] Common side effects include liver problems, nausea, joint pain, and a rash. [7]
Benzbromarone is a uricosuric agent and non-competitive inhibitor of xanthine oxidase [1] used in the treatment of gout, especially when allopurinol, a first-line treatment, fails or produces intolerable adverse effects. It is structurally related to the antiarrhythmic amiodarone. [2]
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