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The Disabled-1 (Dab1) gene encodes a key regulator of Reelin signaling. Reelin is a large glycoprotein secreted by neurons of the developing brain, particularly Cajal-Retzius cells . DAB1 functions downstream of Reln in a signaling pathway that controls cell positioning in the developing brain and during adult neurogenesis .
DAB2 mRNA is expressed in normal ovarian epithelial cells but is down-regulated or absent from ovarian carcinoma cell lines. The 770-amino acid predicted protein has an overall 83% identity with the mouse p96 protein, a putative mitogen-responsive phosphoprotein; homology is strongest in the amino-terminal end of the protein in a region corresponding to the phosphotyrosine interaction domain.
Adapter molecule crk is a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. This protein has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction.
Jennifer Kaye Ringley (born August 10, 1976) [1] is an Internet personality and former lifecaster. She is widely regarded as the first camgirl. She is known for creating the popular website JenniCam. [2] [3] Previously, live webcams transmitted static shots from cameras aimed through windows or at coffee pots. [4]
Myth #1: There’s one virus behind the common cold There’s a reason you might catch a cold multiple times a season — even after it feels like you just got over one, Russo says: They can be ...
And feel free to store any extra brownies in the fridge for up to 7 days. View Recipe. Almond Confetti Mandel Bread. ... Winter Storm Blair live updates: Blizzard warning extended into Kansas City.
A LifeCam HD-3000 webcam sitting on top of a monitor. The LifeCam is a lineup of webcams from Microsoft for PC users marketed since 2006. Various models and series of webcams are designed for either laptops or desktops.
What does the year hold in store, and will 2025 be the comeback year for live music? Way.com looks at what went wrong in 2024 and why it could go right in 2025. 2024 is apparently the year the ...