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The lack of oxygen (hypoxia) causes cell death in a localized area which is perfused by blood vessels failing to deliver primarily oxygen, but also other important nutrients. While ischemia in most tissues of the body will cause coagulative necrosis, in the central nervous system ischemia causes liquefactive necrosis , as there is very little ...
In the arterial system, bubbles (arterial gas embolism) are far more dangerous because they block circulation and cause infarction (tissue death, due to local loss of blood flow). In the brain, infarction results in stroke , and in the spinal cord it may result in paralysis .
Intermittent claudication, also known as vascular claudication, is a symptom that describes muscle pain on mild exertion (ache, cramp, numbness or sense of fatigue), [1] classically in the calf muscle, which occurs during exercise, such as walking, and is relieved by a short period of rest.
“From reports, she was working hard in the months before her death and appeared to be fit and well. However, the chance of having a stroke increases with age and affects women more than men.
The symptoms of claudication ensue when the artery spasms, or clamps down on itself, creating an obstruction. Similar to atherosclerosis, this leads to decreased blood flow to the tissue downstream of the obstruction. Thrombosis, or the formation of a blood clot, usually occurs due to stasis or trauma. [54]
When it comes to a stroke, time matters. Immediate action can prevent brain damage, long-term disability and death. Remember BE FAST acronym.
The prognosis for patients with peripheral vascular disease due to atherosclerosis is poor; patients with intermittent claudication due to atherosclerosis are at increased risk of death from cardiovascular disease (e.g. heart attack), because the same disease that affects the legs is often present in the arteries of the heart. [8]
Men are 25% more likely to develop stroke than women, [53] yet 60% of deaths from stroke occur in women. [233] Since women live longer, they are older on average when they have stroke and thus more often killed. [53] Some risk factors for stroke apply only to women. Primary among these are pregnancy, childbirth, menopause, and the treatment thereof